Description

NerveReverse

NerveReverse  A Complete Formula for Nerve Health

NerveReverse is The Most Complete Nerve Supplement on the market.

• 5000 IU Vitamin D3 – Restoring Vitamin D levels has been shown to significantly improve neuropathy symptoms. Improves immune system.
• 30 mg Pyridoxal-5-Phosphate(B6) – An enhanced form of B6 that when coupled with other B vitamins has been shown to improve nerve fiber density and other neuropathy scores.
• 2mg L-Methylfolate(B9) – Up to 50% of people’s bodies cannot break down folic acid due to a gene mutation (MTHFR gene). Using a methylated form bypasses this mutation so your body gets what it needs.
• 2mg Methylcobalamin(B12) – Metformin, a commonly used drug to treat diabetes, inhibits B12 absorption which is why up to 30% of Metformin users have a B12 deficiency. Using a Methylated B12 helps restore these levels.
• 300mg Benfotiamine(B1) – Fat-soluble form of B1 that has been used in Europe for many years to treat neuropathy.
• 250mg Alpha Lipoic Acid – An antioxidant that reduces oxidative stress and inflammation surrounding the nerves.

NerveReverse ingredients and Clinical Studies

Vitamin D

Vitamin D deficiency has been linked to diabetes and neuropathy. High doses of Vitamin D have been shown to improve symptoms associated with neuropathy.

1. 81% of patients with neuropathy had Vitamin D deficiency compared with 60% of those without neuropathy. View Study
2. Vitamin D3 supplementation improved symptoms of neuropathy. View Study
3. A 3 year national study shows that a significant number of patients with diabetic neuropathy suffered from Vitamin D deficiency. View Study
4. Type 2 diabetics had lower pain scores after 3 month supplementation of Vitamin D. View Study
5. High dose Vitamin D supplementation in patients with painful diabetic neuropathy is associated with a significant decrease in symptoms. View Study

Vitamin B12

It is widely accepted that a B12 deficiency damages the myelin sheath that surrounds and protects nerves. B12 supplementation is an essential part of preventing and treating nerve damage, especially diabetic neuropathy.

1. Metformin, the most commonly used drug for the treatment of diabetes causes malabsorption of folic acid and B12, which worsens neuropathy symptoms.
   https://www.ncbi.nlm.nih.gov/pubmed/19846797
   http://www.bmj.com/content/340/bmj.c2181
   View Study
2. Researchers have demonstrated that Vitamin B12 and folate deficiency are associated with increased levels of homocysteine, increased oxidative stress, and decreased antioxidant activity. View Study
3. 62 percent of patients that have diabetic neuropathy, have a B12 deficiency. The administration of B12 reversed the deficiency. View Study
4. Methylcobalamin improves sensory and autonomic nerve dysfunction. View Study
5. Symptoms of neuropathy significantly improved with daily dose of 1500mcg methylcobalamin for 24 weeks. View Study
6. Effects of Methylcobalamin on diabetic peripheral neuropathy. View Study

Folate

Over half of the US population suffers from a gene mutation called MTHFR which inhibits the body’s ability to convert the folate from food into the metabolite our body can use. This can cause problems and can lead to an increased risk of disease due to unmetabolized folic acid in the body. NerveReverse uses a special form of Folic Acid called 5-MTHF or L-Methylfolate which bypasses this mutation effect to give the body what it needs without having to convert it to useable form.

1. Folic Acid handling by the human gut: implications for food fortification and supplementation. View Study
2. Is Folic Acid Good for Everyone?  This study shows that high levels of unmetabolized folic acid in the blood could be dangerous.  This is why it’s important to take L-Methylfolate which is already metabolized.    View Study
3. Low-dose L-MTHF is equally (if not more) effective as is folic acid in reducing homocysteine concentrations in healthy persons.  View Study
4. Nutritional Management of patients with diabetic peripheral neuropathy with 5-MTHF-methylcobalamin-pyridoxal-5-phosphate: results of a real-world patient experience trial. View Study
5. MTHF increases plasma folate more effectively than folic acid in women with MTHFR. View Study
6. Folate, folic acid and 5-MTHF are not the same thing. View Study